Skip to main content

Table 2 The top 20 clusters and their representative enriched terms (one per cluster)

From: ENPP1 deletion causes mouse osteoporosis via the MKK3/p38 MAPK/PCNA signaling pathway

Description

Count

%

Log10(P)

Log10(q)

MAPK signaling pathway

20

86.96

− 37.95

− 33.89

Ras signaling pathway

9

39.13

− 12.52

− 8.76

PID TNF PATHWAY

6

26.09

− 11.87

− 8.29

Regulation of kinase activity

11

47.83

− 11.26

− 7.74

VEGFA-VEGFR2 signaling pathway

9

39.13

− 10.47

− 7.11

Osteoclast differentiation

6

26.09

− 9.09

− 6.05

Positive regulation of cell migration

8

34.78

− 8.08

− 5.17

Focal adhesion

6

26.09

− 7.98

− 5.12

ST P38 MAPK PATHWAY

4

17.39

− 7.66

− 4.9

Signaling by receptor tyrosine kinases

7

30.43

− 6.87

− 4.21

VEGF signaling pathway

4

17.39

− 6.83

− 4.19

Platelet activation, signaling, and aggregation

5

21.74

− 5.7

− 3.23

Actin filament-based process

7

30.43

− 5.63

− 3.18

Cell junction organization

6

26.09

− 4.81

− 2.5

Apoptosis modulation and signaling

3

13.04

− 4.23

− 2.08

Hippo signaling regulation pathways

3

13.04

− 4.15

− 2.02

Muscle structure development

5

21.74

− 3.86

− 1.79

Negative regulation of secretion by cell

3

13.04

− 3.64

− 1.61

Oxytocin signaling pathway

3

13.04

− 3.6

− 1.57

Regulation of cell activation

4

17.39

− 2.76

− 0.86

  1. “Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%” is the percentage of all the user-provided genes that are found in the given ontology term. (Only input genes with at least one ontology term annotation are included in the calculation.) “Log10(P)” is the p value in log base 10. “Log10(q)” is the multi-test adjusted p value in log base 10