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Table 1 Trabecular bone parameters in the distal femur of 12-week WT and KO mice

From: ENPP1 deletion causes mouse osteoporosis via the MKK3/p38 MAPK/PCNA signaling pathway

 

WT

KO

p value

Parameters of µCT

BV/TV (%)

6.967 ± 0.256

1.287 ± 0.220

< 0.0001

Tb. Th(mm)

0.043 ± 0.003

0.037 ± 0.001

0.0441

Tb. N(mm−1)

1.651 ± 0.078

0.372 ± 0.020

 < 0.0001

Tb. Sp(mm)

0.255 ± 0.009

0.449 ± 0.042

0.0014

Connectivity

231.333 ± 11.060

104.000 ± 14.422

0.0003

Tb. Pf(mm−1)

33.477 ± 0.950

60.404 ± 2.033

 < 0.0001

SMI

2.259 ± 0.111

2.703 ± 0.123

0.0096

  1. Parameters were expressed as mean ± standard deviation, and comparisons between the two groups were performed using the Student’s t test
  2. p value with statistical significance was labeled in bold
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X