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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: LncRNA CASC9 promotes cell proliferation and invasion in osteosarcoma through targeting miR-874-3p/SOX12 axis

Fig. 4

LncRNA CASC9/miR-874-3p directly targeted SOX12 in OS. A The binding sites of SOX12 on miR-874-3p were predicted by TargetScan. B The binding of SOX12 and miR-874-3p was verified by luciferase reporter assay. C The expression levels of SOX12 in 30 pairs of OS tumor tissues and normal tissues were detected using qRT-PCR. D The relationship between lncRNA CASC9 expression and SOX12 expression was calculated using Pearson’s χ2 test. E The relationship between SOX12 expression and miR-874-3p expression was calculated using Pearson's χ2 test. F, G The expression of SOX12 was assessed using Western blot. **represented P < 0.01

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