Fig. 5

HE staining in each group at three time points. After 4 weeks, 8 weeks, and 12 weeks of the experiment, the HE-stained images of the defect areas were observed under a light microscope at ×40 and ×200 magnification. Black arrows indicate areas of inflammation and green arrows indicate neovascularization. Black arrows—Indicates osteoblast, yellow arrows—Indicates Inflammatory cells, green arrows—Indicates neovascularization, red arrows—Indicates Bone cells, white arrows —Indicates Immature bone tissue