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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Tourniquet use following blast-associated complex lower limb injury and traumatic amputation promotes end organ dysfunction and amplified heterotopic ossification formation

Fig. 4Fig. 4

Elevated and prolonged systemic inflammatory response occurs following tourniquet application to a complex injured limb. Graphs show serum concentrations of A cytokines, B chemokines, and C growth factors between 6 h and Day 7 post injury in the Blast Complex Control and Blast Complex HLI 150-min groups. Graphs shown as mean and 95% CI with statistical testing using two-way ANOVA with Holm-Sidak corrected for multiple comparisons. Shaded horizontal band denotes the 95% CI of the mean serum concentrations of analytes in the naïve group. Significance shown as *p < 0.05; **p < 0.01; ***p < 0.001, ns not significant

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