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Table 2 Clinical outcomes for each study

From: Unicompartmental knee arthroplasty is associated with lower pain levels but inferior range of motion, compared with high tibial osteotomy: a systematic overview of meta-analyses

Author/Year

Clinical and functional results

Revision rates

Complications rates

Effect size [95% CI]

P value

na

For

Effect size [95% CI]

P value

na

For

Effect size [95% CI]

P value

na

For

Migliorini et al. [7]

Tegner

MD 0.69

[0.03–1.35]

.04

 

UKA

5 years revision rate

OR 2.27 [0.50–10.34]

.004

 

UKA

     

Lysholm

MD 3.07 [1.19–4.95]

.001

 

UKA

Kaplan‒Meier curve

 

.01

 

UKA

     

IKDC

MD 8.89 [4.29–13.48]

.0001

 

UKA

          

KOOS

MD 2.27 [− 4.23–8.77]

.05

 

UKA

          

Bai et al. [35]

Tegner

MD 0.00 [-0.18–0.18]

.97

5

n.s

Revision rate

OR 1.17 [0.48–2.82]

.73

4

n.s

Total Complications rate

OR 0.51 [0.24–1.07]

0.07

9

n. s

Lysholm

MD 0.84 [0.29–1.39]

.003

6

UKA

     

Infection rate

OR 0.91 [0.24–3.50]

0.89

4

n. s

E/G results

OR 1.34 [0.49–3.67]

.57

4

n.s

          

ROM

MD − 5.47 [− 9.53 to − 1.41]

.008

7

HTO

          

Huang et al. [17]

HSS

MD 1.25 [− 3.70–1.20]

.32

3

n.s

Revision rate

OR 0.38 [0.07–1.89]

.23

4

n.s

Total Complications rate

OR 1.11 [0.49–12.49]

0.81

7

n.s

Lysholm

MD − 0.90 [− 3.70–1.89]

.53

2

n.s

          

ROM

MD 10.18 [2.49–17.86]

.009

3

HTO

          

velocity

MD 0.02 [− 0.09–0.04]

.49

3

n.s

          

Cao et al. [3]

Lysholm

MD 4.99 [− 3.91–13.09]

.27

2

n.s

Revision rate

OR 0.52 [0.30–0.90]

.02

8

UKA

Complications (total)

OR 0.42 [0.20–0.89]

0.02

5

UKA

KSS

MD − 4.03 [− 9.91–1.85]

.18

2

n.s

     

Complications (RCT)

OR 0.20 [0.04–1.00]

0.05

1

UKA

E/G results

OR 2.18 [0.58–8.23]

.25

4

n.s

     

Complications (n-RCT)

OR 0.54 [0.22–1.30]

0.17

4

n.s

ROM

SMD − 0.85[− 1.43 to − 0.27]

0.04

4

HTO

          

Pain

OR 5.65 [1.24–25.81]

.03

2

UKA

          

Santoso et al. [5]

Knee scores b

STD − 0.21 [− 0.47–0.05]

0.11

7

n.s

Revision rate

OR 1.18 [0.54–2.58]

0.68

11

n.s

Complications rate

OR 3.08 [1.76–5.39]

 < 0.0001

7

UKA

E/G results

OR 0.37 [0.24–0.58]

 < 0.00001

10

UKA

          

Subgroup: E/G CW-HTO-UKA

OR 0.36 [0.21–0.61]

0.01

6

UKA

          

Subgroup: E/G OW-HTO-UKA

OR 0.70 [0.26–1.91]

0.49

3

n.s

          

ROM

SMD 0.78 [0.21, 1.36]

0.008

5

HTO

          

Velocity

SMD − 0.09 [− 0.48, 0.30]

0.66

3

n.s

          

Pain

OR 0.34 [0.13, 0.91]

0.03

5

UKA

          

Han et al. [19]

E/G results

OR 0.47 [0.24–0.95]

0.04

10

UKA

Revision–TKA (total)

OR 1.56 [0.61–3.98]

0.35

7

n.s

Complications rate

OR 2.48 [1.26 to 4.90]

0.009

8

UKA

ROM

MD 8.62 [2.02–15.23]

0.01

6

HTO

Subgroup: CW-HTO vs. UKA

OR 2.38 [1.05–5.42]

0.04

4

UKA

     

Pain

OR 0.28 [0.12–0.62]

0.002

4

UKA

Subgroup: OW-HTO vs. UKA

OR 0.24 [0.03–2.00]

0.19

3

n.s

     

Velocity

MD − 0.05 [− 0.11 to − 0.00]

0.03

4

UKA

          

Fu et al. [21]

Knee scoresc

SMD 0.78 [− 0.75, 2.30]

0.32

4

n.s

Revision rate

OR 0.82 [0.30–2.21]

0.69

7

n.s

Complication rate

OR 2.00 [0.62, 6.50]

0.25

4

n.s

E/G results

OR 0.43 [0.26, 0.69]

0.0006

8

UKA

          

ROM

SMD 1.36 [1.05, 1.67]

 < 0.00001

5

HTO

          

Velocity

SMD − 0.49 [− 0.98, 0.01]

0.05

3

UKA

          

Spahn et al. [6]

Fu et al. [21]

normalized knee scoresd

   

Survival to endpoint TKA rate

   

Complication rate

      

5–8 years of follow-up

HTO 83.4 [82.6–84.2]

 < 0.001

7

UKA

5–8 years of follow-up

HTO 0.910 [0.882–0.932]

0.801

30

n.s

HTO 0.138 [0.107, 0.177]

UKA 0.113 [0.079, 0.168]

0.369

UKA 31/HTO 13

n.s

 

UKA 91.2 [90.9–91.4]

 

5

  

UKA 0.915 [0.882–0.939]

 

26

      

9–12 years of follow-up

HTO 79.9 [76.9, 82.8]

 < 0.001

7

UKA

9–12 years of follow-up

HTO 0.844 [0.797–0.882]

0.458

28

n.s

     
 

UKA 90.0 [89.7, 90.2]

 

5

  

UKA 0.869 [0.814–0.909]

 

25

      

After more than 12 years of follow-up

HTO 58.8 [47.6, 69.9]

0.331

2

n.s

More than 12 years of follow-up

HTO 0.701 [0.605–0.782]

0.451

15

n.s

     
 

UKA 65.6 [57.4, 73.9]

 

3

  

UKA 0.775 [0.583–0.895]

 

9

      

Knee score from baseline to 5–8 years of follow-up

HTO SMD 5.0 [3.2–6.8]

0.359

7

n.s

Mean survival (Kaplan–Maier)

HTO 9.7 years [8.1–11.2]

0.374

12

n.s

     
 

UKA SMD 4.1 [3.2–4.7]

 

3

  

UKA 8.2 years [5.5–11.0]

 

5

      

Knee score from baseline to 9–12 years of follow-up

HTO 1.7 [1.0, 2.3]

 < 0.001

8

UKA

          
 

UKA 10.7 [10.2, 11.1]

 

1

           

Score from baseline to more than 12 years of follow-up

HTO -0.2 [− 0.5, 0.1]

0.603

1

n.s

          
 

UKA 1.2 [0.7, 1.6]

 

1

           

Zhang et al. [16]

E/G result

OR 2.43 [1.46, 4.05]

0.0006

6

UKA

Revision rate

OR 0.47 [0.23–0.97]

0.04

5

UKA

Complication rate

OR 0.24 [0.10, 0.56]

0.001

4

UKA

Gandhi et al. [20]

E/G result

OR 2.03 [1.16–3.6]

0.013

6

UKA

survival from aseptic loosening

OR 2.14 [0.93–4.93]

0.074

5

n.s

     

Velocity

SMD 0.389 [− 0.124–0.902]

0.137

2

n.s

          
  1. UKA Unicompartmental knee arthroplasty, HTO High tibial osteotomy, n.s. Not significant, CI Confidence interval, SMD Standard mean difference, MD Mean difference, RR Relative risk, OR Odds ratio, E/G result Excellent and good functional results, Tegner Tegner activity scale, Lysholm Lysholm Knee Score, KSS Knee Society Score, IKDC International Knee Documentation Committee, KOOS Knee Injury and Osteoarthritis Outcome Score, HSS Hospital for Special Surgery Score, ROM range of motion
  2. aNumber of studies reporting on an outcome
  3. bKnee scores included the Baily Knee Score, Knee Society Score, British Orthopaedic Association Score, and Hospital for Special Surgery Score
  4. cKnee scores included the Lysholm Knee Score and the Knee Society Score
  5. dEach study used a self-created 100-point score
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X