Fig. 1
From: Circ_0136666 aggravates osteosarcoma development through mediating miR-1244/CEP55 axis
Circ_0136666 expression is prominently elevated in OS tissues and cell lines. A Circ_0136666 is derived from the back-splicing of exon 68, 69, and 70 in PRKDC gene. B RT-qPCR was applied to determine the expression of circ_0136666 in OS tissues (n = 41) and adjacent normal tissues (n = 41). C The level of circ_0136666 was examined in hFOB 1.19 and two OS cell lines (U2OS and SaOS2) by RT-qPCR. D and E The RNase R resistance of circ_0136666 and its linear form PRKDC mRNA was analyzed by RT-qPCR. ***P < 0.001