References | Country | Design/level of evidence | Sample size (PRP/control) | BMI | Mean age (years) | Gender (M/F) | PRP preparation | PRP injection protocol | PRP/PRFM | LR/LP | Follow-up (months) |
---|---|---|---|---|---|---|---|---|---|---|---|
Yang et al. [26] | China | Retrospective comparative trial/III | 61 (30/31) | 25.2 | 36.4 | 44/17 | Regen Kit | Multiple intra-articular injection after surgery | PRP | NR | 33 |
Bailey et al. [25] | America | Retrospective matched case–control study/III | 324 (162/162) | 25.6 | 22.2 | 192/132 | Angel double-spin, concentrated PRP system | Intraoperative administration | PRP | LR | 24 |
Kaminski et al. [34] | Poland | Prospective, randomized, placebo-controlled, double-blind study/I | 72 (42/30) | 27.4 | 44.8 | 41/31 | Activated using autologous thrombin | Minimally invasive intrameniscal application (6–8 mL) | PRP | LR | 23 |
Everhart et al. [33] | America | Cohort study/III | 550 (203/347) | 27.6 | 28.8 | 348/202 | GPS III system and Angel system | Introduced into the joint before closure (5Â mL) | PRP | LR | 36 |
Dai et al. [19] | China | Retrospective cohort/III | 29 (14/15) | NR | 31.3 | 11/18 | Sodium citrate as anticoagulant | Injected on the repaired site under arthroscope (4Â mL) | PRP | LR | 20.6 |
Kemmochi et al. [32] | Japan | Prospective, interventional, non-randomized trial/II | 22 (17/5) | NR | 29.8 | 12/10 | PRF box | Inserted into the cleft of the injured meniscus (2.4Â cm3) | PRFM | LR | 6 |
Kaminski et al. [31] | Poland | Prospective, randomized, double-blind, placebo-controlled, parallel-arm study/I | 37 (19/18) | NR | 28.1 | 30/7 | ELISA and blood analyzer; Activated using autologous thrombin | Injected into meniscal repair site (8Â mL) | PRP | LR | 54 |
Pujol et al. [30] | France | Retrospective cohort/III | 34 (17/17) | NR | 30.3 | 24/10 | GPS III system | In situ injection after mini-arthrotomy (5Â mL) | PRP | LR | 32.2 |
Griffin et al. [20] | America | Retrospective cohort /III | 35 (15/20) | 25 | 31.0 | 28/7 | Cascade Platelet-Rich Fibrin Matrix | Sutured into meniscal repair site | PRFM | NR | 48 |