Patient or Population: Patients with primary total knee arthroplasty Setting: postoperative care in hospital, Egypt (1 trial), India (2 trials), America (3 trials), Thailand (3 trials), China (4 trials) Intervention: The interspace between the popliteal artery and capsule of the knee, IPACK Comparison: Non-IPACK | |||||
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Outcome indicator | Importance | Relative effect (95%CI) | No. of Participants (studies) | Quality of the evidence | Comments |
Pain at rest (6–12 h) | Critical | − 0.960 (− 1.467, − 0.454) | 1309 (13) | ⊕⊕⊕○ Moderate a | inconsistency |
Pain at ambulation (6–12 h) | Important | − 0.691 (− 1.064, − 0.318) | 1223 (13) | ⊕⊕⊕○ Moderate b | inconsistency |
Morphine consumption (24–48 h) | Critical | − 2.979 (− 5.714, − 0.244) | 812 (10) | ⊕⊕⊕⊕ High | inconsistency |
Morphine requirement (12–24 h) | Important | 0.506 (0.309, 0.829) | 281 (4) | ⊕⊕⊕○ Moderate | inconsistency |
Ambulation distances (POD2) | Important | 1.743 (0.339, 3.147) | 439 (5) | ⊕⊕⊕○ Moderate | inconsistency |
Sleep disturbance (POD1) | Important | 0.388 (0.185, 0.812) | 264 (4) | ⊕⊕⊕○ Moderate | Small number of participants |