Fig. 4

Circ_0008365 alleviated IL-1β-induced CHON-001 cell damage by binding to miR-338-3p. A–E IL-1β-induced CHON-001 cells were transfected with pcDNA, circ_0008365, circ_0008365 + miR-NC or circ_0008365 + miR-338-3p; A The viability of cells was examined by CCK-8; B EDU assay was conducted to detect cell proliferation; C The apoptosis of cells was measured by Flow cytometry analysis; D, E Western blot analysis was used to determine protein levels. **P < 0.01, ***P < 0.001