Fig. 3From: The role of the Smad2/3/4 signaling pathway in osteogenic differentiation regulation by ClC-3 chloride channels in MC3T3-E1 cellsThe effects of ClC-3 chloride channels on the nuclear translocation of Smad2/3/4. The formation of the Smad2/3/4 complex when ClC-3 and TβR were inhibited is shown (a), and the results were confirmed by quantitative densitometric analysis (b). The results of immunofluorescence analysis of Smad4 and quantification of the data are shown (c). Scale bars = 50 μm. *P < 0.05 compared with the control groupBack to article page