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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Circ-FOXM1 promotes the proliferation, migration and EMT process of osteosarcoma cells through FOXM1-mediated Wnt pathway activation

Fig. 2

Knockdown of circ-FOXM1 suppressed OS cell proliferation, migration and EMT process. a The inference efficacy of sh-circ-FOXM1#1/2/3 in two OS cells was determined by qRT-PCR. b, c Cell proliferation was measured through CCK-8 and EdU (bar value = 50 μm) assays in sh-circ-FOXM1-transfected cells. d Cell apoptosis was estimated by the use of TUNEL (bar value = 50 μm) assay in sh-circ-FOXM1-transfected cells. e Transwell (bar value = 50 μm) assay was performed to evaluate cell migration in sh-circ-FOXM1-transfected cells. f The levels of EMT-associated proteins were measured using western blot in sh-circ-FOXM1-transfected cells. **P < 0.01

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