Table 2 Docking score of compounds with each core target
Compound | Structure | Docking score/(kcal mol−1) | |||
|---|---|---|---|---|---|
AKT1 | FOXO1 | PI3K | VEGFA | ||
Beta-sitosterol |
| − 11.7 | − 6.5 | − 9.0 | − 7.2 |
Stigmasterol |
| − 11.9 | − 6.7 | − 9.3 | − 7.6 |
Diosgenin |
| − 13.3 | − 7.5 | − 8.2 | − 9.2 |
Tetrahydroalstonine |
| − 9.1 | − 7.6 | − 9.0 | − 8.3 |
Kadsurenone |
| − 9.5 | − 6.6 | − 8.0 | − 7.4 |
