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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: EBF1-mediated up-regulation of lncRNA FGD5-AS1 facilitates osteosarcoma progression by regulating miR-124-3p/G3BP2 axis as a ceRNA

Fig. 1

G3BP2 expression is up-regulated in osteosarcoma cells and facilitates the cell malignancy of osteosarcoma. A RT-qPCR of G3BP2 expression in osteosarcoma cell lines in contrast to normal osteoblast cell line. B RT-qPCR was taken to measure G3BP2 inhibition efficiency. C–D The proliferation of osteosarcoma cells after G3BP2 inhibition was analyzed by immunofluorescence (×20 magnified) as well as colony formation assays. E–G JC-1 (×100 magnified), TUNEL (×100 magnified) assay and caspase-3/8/9 assay were taken to evaluate cell apoptosis rate when G3BP2 was silenced. H Transwell assays (×100 magnified) measured cell invasion after G3BP2 was suppressed. *P < 0.05, **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X