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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Roxadustat promotes osteoblast differentiation and prevents estrogen deficiency-induced bone loss by stabilizing HIF-1α and activating the Wnt/β-catenin signaling pathway

Fig. 2

Roxadustat upregulated the expression levels of osteogenic markers in osteoblasts. A The mRNA expression levels of osteogenic markers in osteoblasts at day 7. B The protein expression levels of osteogenic markers in osteoblasts at day 7. Data are presented as the mean ± SD of three independent experiments; *P < 0.05, **P < 0.01, compared with the control group

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