Table 4 The characteristics of the studies about human
From: MicroRNA-143 expression inhibits the growth and the invasion of osteosarcoma
References | Country | Number | Gender(F/M) | Age (H /L) | Anatomical site(H /L) | Outcomes |
|---|---|---|---|---|---|---|
Zhao [25] | China | High level: 58 Low level: 36 | High level:27/31 Low level: 17/19 | 28 patients ≤ 20 years, 34 patients > 20 years/ 13 patients ≤ 20 years, 19 patients > 20 years | 22 in femur, 28 in tibia, 9 in others/13 in femur, 21 in tibia, 5 in others | Tumor size, Tumor size, Metastasis |
Sun [7] | China | High level: 10 Low level: 23 | High level: 4/6 Low level: 12/11 | 7 patients ≤ 20 years, 3 patients > 20 years/ 15 patients ≤ 20 years, 7 patients > 20 years | 5 in femur, 2 in tibia,2 in humerus,1 in others/17 in femur, 10 in tibia, 4 in humerus,2 in others | Tumor size, Tumor grade, Survival curve, expression level of miR-143 |
Dong [15] | China | High level: 19 Low level: 9 | High level: 11/8 Low level: 3/6 | 11 patients < 18 years, 8 patients ≥ 18 years / 4 patients < 18 years, 5 patients ≥ 18 years | NR | Tumor size, Tumor grade, Metastasis, Recurrence |
Hirahata [4] | Japan | High level: 3 Low level: 19 | NR | NR | NR | Metastasis |
Liu [29] | China | A total of 5 patients | NR | NR | NR | Expression level of miR-143 |
Zhou [30] | China | High level:20 Low level: 25 | NR | NR | NR | Survival curve, Expression level of miR-143 |
Chen [40] | China | No metastasis: 35 Metastasis: 31 | High level: 13 Low level: 15 | NR | NR | Expression level of miR-143 |
Wang [33] | China | A total of 18 patients | NR | NR | NR | Expression level of miR-143 |
Wen [1] | China | 20 cisplatin-sensitive and 20 cisplatin-resistant patients | NR | NR | NR | Expression level of miR-143 |
Li [28] | China | 25 pair tissues | NR | NR | NR | Expression level of miR-143 |
Osaki [37] | Japan | No metastasis: 15 Lung metastasis: 7 | NR | NR | NR | Expression level of miR-143, Metastasis |