MicroRNA-143 expression inhibits the growth and the invasion of osteosarcoma

Table 3 The characteristics of the studies about mice

Studies	Characteristics of animals	Animal groups	OS xenograft methods	Experimental Groups (miR-143 overexpressed)	Control groups	Outcomes
Sun [7]	BALB/c nude mice (4 weeks)	6/6	Subcutaneous	143B + miR-143	143B + NC	Tumor volume Tumor weight Mice survival number
Li [28]	male BALB/c nude mice (4–6 weeks)	4/4	Subcutaneous	U2-OS + miR-143	U2-OS + control	Tumor volume Tumor weight
Zhou [30]	Balb/C nude mice (about 20 g)	9/9/9/9	Subcutaneous	U2-OS + miR-143	U2-OS + NC U2-OS + Dox U2-OS + miR-143 + DOX	Tumor weight
Zhou [30]	Balb/C nude mice (about 20 g)	9/9/9/9	Subcutaneous	SAOS-2 + miR-143	SAOS-2 + NC SAOS-2 + Dox SAOS-2 + miR-143 + DOX	Tumor weight
Osaki [37]	athymic mice	10/10	Intratibial	143B + miR-143	143B + NC	Tumor weight Mice survival number
Zhang [38]	female BALB/c athymic nude mice (4 weeks)	6/6	Subcutaneous	MG63 + miR-143	MG63 + NC	Tumor volume
Zhang [38]	female BALB/c athymic nude mice (4 weeks)	6/6	Subcutaneous	U2-OS + miR-143	U2-OS + NC	Tumor volume

ISSN: 1749-799X