Fig. 4

A–D PVT1 and miR-140 were co-localized in chondrocytes by FISH. A PVT1 was stained green; B miR-140 was stained red; C cell nuclei were stained blue; D overlapped expression was mixed (scale bar, 20 μm). E Relative lncRNA PVT1 expression was detected in Biotin-miR-140 group compared with Biotin-NC group. F Relative miR-140 expression was detected in Biotin-PVT1 group compared with Biotin-NC group. The results were represented as mean ± SD. **P < 0.01 vs Biotin-NC (E, F)