Fig. 2

HMGB-1 deficiency inhibits the osteoclastogenesis after OVX. a, b The numbers of TRAP-positive cells were detected with TRAP staining in all the rats. Data are from three independent experiments. c, d The expressions of OSCAR and TRAP are detected though qRT-PCR and western blotting. Error bars indicate SD. *P < 0.05 vs WT Sham group, ^#P < 0.05 vs WT OVX group. n = 6. Data are from four independent experiments