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Table 5 Pearson’s correlation coefficients between bone mass parameters, trabecular microarchitecture parameters, and mechanical behavior

From: Breaking strength and bone microarchitecture in osteoporosis: a biomechanical approximation based on load tests in 104 human vertebrae from the cervical, thoracic, and lumbar spines of 13 body donors

  BMD HU BVF Tb.Th Tb.Sp DA Tb.N Tb.Pf Conn.D Failure load Failure stress
BMD (mg/cm3)            
HU 0.74**           
BVF (%) 0.76** 0.86**          
Tb.Th (µm) 0.55 0.81** 0.82**         
Tb.Sp (µm) − 0.23 − 0.05 − 0.34 − 0.26        
DA (n) − 0.19 − 0.67 − 0.54 − 0.61* − 0.30       
Tb.N (n/mm) 0.60* 0.48 0.71** 0.51 − 0.85** − 0.01      
Tb.Pf(mm−1) − 0.62* − 0.84** − 0.85** − 0.67* 0.09 0.71** − 0.54     
Conn.D(mm−3) 0.43 0.52 0.66* 0.49 − 0.39 − 0.37 0.46 − 0.41    
Failure load (N) 0.52 0.70** 0.67* 0.58* − 0.04 − 0.51 0.46 − 0.81** 0.05   
Failure strength (N/mm2) 0.56* 0.86** 0.76** 0.83** − 0.09 − 0.64* 0.49 − 0.79** 0.19 0.84**  
  1. BMD, bone mineral density; HU, Hounsfield units; BVF, bone volume fraction; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation, DA, degree of anisotropy; Tb.N, trabecular number; Tb.Pf, trabecular pattern factor; and Conn.D, connectivity density
  2. *p < 0.05; **p < 0.01; and ***p < 0.001