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Table 2 Descriptive statistics for microcomputed tomography parameters

From: Breaking strength and bone microarchitecture in osteoporosis: a biomechanical approximation based on load tests in 104 human vertebrae from the cervical, thoracic, and lumbar spines of 13 body donors

 

Spinal section

Group comparison

Architectural parameter

Group

Total

CS

TS

LS

CS vs. TS

p value

CS vs. LS

p value

TS vs. LS

p value

BVF (%)

Total

18.09 ± 2.97

22.79 ± 2.22

17.09 ± 1.17

15.79 ± 0.74

0.023P

0.001P

0.401P

Male

18.95 ± 4.76

26.33 ± 4.81

16.57 ± 1.34

17.27 ± 1.50

0.002P

0.085P

1.000P

Female

17.71 ± 2.53

21.22 ± 1.77

17.33 ± 1.32

15.13 ± 1.22

0.055P

0.001P

0.124P

 ≤ 1Fx

20.43 ± 3.75

25.76 ± 4.28

19.36 ± 1.43

17.66 ± 1.20

0.070P

0.002P

0.196P

 ≥ 2Fx

16.09 ± 2.64

20.24 ± 1.32

15.15 ± 1.43

14.19 ± 0.67

0.015P

0.002P

0.569P

Tb.Th (µm)

Total

182 ± 9

191 ± 10

180 ± 6

177 ± 7

0.008L

0.006L

0.477L

Male

184 ± 21

211 ± 19

178 ± 14

171 ± 12

0.001L

0.001L

0.446L

Female

181 ± 7

182 ± 10

181 ± 6

179 ± 7

   

 ≤ 1 Fx

189 ± 13

202 ± 16

188 ± 9

179 ± 7

0.026L

0.003L

0.116L

 ≥ 2 Fx

175 ± 9

182 ± 9

172 ± 9

175 ± 9

   

Tb.Sp (µm)

Total

854 ± 91

729 ± 60

874 ± 59

933 ± 37

 < 0.001L

 < 0.001L

0.060L

Male

901 ± 152

687 ± 103

969 ± 102

950 ± 90

 < 0.001L

0.001L

0.717L

Female

834 ± 91

748 ± 47

831 ± 81

925 ± 61

0.038L

0.001L

0.022L

 ≤ 1 Fx

815 ± 114

683 ± 90

836 ± 99

897 ± 38

0.004L

0.001L

0.206L

 ≥ 2 Fx

888 ± 92

768 ± 52

906 ± 58

963 ± 80

0.001L

 < 0.001L

0.098L

DA (n)

Total

0.33 ± 0.04

0.29 ± 0.03

0.33 ± 0.04

0.34 ± 0.03

   

Male

0.32 ± 0.06

0.28 ± 0.07

0.33 ± 0.05

0.33 ± 0.05

   

Female

0.33 ± 0.04

0.30 ± 0.02

0.33 ± 0.04

0.35 ± 0.02

   

 ≤ 1 Fx

0.31 ± 0.05

0.28 ± 0.05

0.32 ± 0.05

0.31 ± 0.02

   

 ≥ 2 Fx

0.34 ± 0.04

0.31 ± 0.03

0.34 ± 0.04

0.36 ± 0.03

   

Tb.N (n/mm)

Total

0.87 ± 0.14

1.09 ± 0.09

0.81 ± 0.07

0.78 ± 0.05

0.014P

0.005P

1.000P

Male

0.91 ± 0.21

1.20 ± 0.19

0.79 ± 0.12

0.90 ± 0.12

0.002P

0.293P

0.394P

Female

0.85 ± 0.13

1.04 ± 0.07

0.83 ± 0.08

0.73 ± 0.02

0.037P

 < 0.001P

0.114P

 ≤ 1 Fx

1.01 ± 0.19

1.27 ± 0.15

0.94 ± 0.15

0.92 ± 0.06

0.015P

0.051P

1.000P

 ≥ 2 Fx

0.75 ± 0.12

0.94 ± 0.07

0.70 ± 0.05

0.66 ± 0.07

0.015P

0.002P

0.569P

Tb.Pf

(mm−1)

Total

5.91 ± 0.96

4.59 ± 0.60

6.13 ± 0.60

6.69 ± 0.61

 < 0.001L

 < 0.001L

0.097L

Male

4.95 ± 1.17

3.32 ± 0.94

5.32 ± 0.78

5.69 ± 0.53

 < 0.001L

 < 0.001L

0.373L

Female

6.33 ± 0.98

5.16 ± 0.47

6.49 ± 0.73

7.13 ± 0.86

0.002L

 < 0.001L

0.109L

 ≤ 1 Fx

4.94 ± 1.10

3.56 ± 0.85

5.07 ± 0.78

5.99 ± 0.39

0.001L

 < 0.001L

0.030L

 ≥ 2 Fx

6.74 ± 0.92

5.48 ± 0.45

7.04 ± 0.55

7.29 ± 0.86

 < 0.001L

 < 0.001L

0.449L

Conn.D

(mm−3)

Total

5.60 ± 1.41

7.55 ± 1.29

4.96 ± 0.85

5.19 ± 0.76

 < 0.001P

0.001P

0.662P

Male

5.25 ± 2.20

7.44 ± 2.56

3.95 ± 1.05

6.18 ± 1.90

0.001P

0.244P

0.021P

Female

5.76 ± 1.45

7.59 ± 1.38

5.42 ± 1.06

4.75 ± 0.42

0.001P

 < 0.001P

0.243P

 ≤ 1 Fx

6.12 ± 1.93

8.03 ± 2.07

5.40 ± 1.67

5.93 ± 1.17

0.008P

0.061P

0.558P

 ≥ 2 Fx

5.16 ± 1.50

7.13 ± 1.32

4.59 ± 1.03

4.55 ± 0.94

 < 0.001P

0.001P

0.943P

  1. Values are presented as means ± SD. CS, cervical spine; TS, thoracic spine; LS, lumbar spine; BVF, bone volume fraction; Tb.Th, trabecular bone thickness; Tb.Sp, trabecular separation; DA, degree of anisotropy; Tb.N, trabecular number; Tb.Pf, trabecular pattern factor; Conn.D, connectivity density; Fx, fracture; P, pairwise comparison; and L, post hoc LSD test; in the absence of F test significance, no pairwise comparisons were tested