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Table 3 Diagnostic performance of the tested markers

From: Diagnostic value of platelet indices in infected nonunion: a retrospective study

Variables

AUC (95% CI)

Optimal cutoff value

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

WBC

0.632 (0.562–0.702)

8.05 × 109/L

38.54

86.07

56.92

74.57

PC

0.769 (0.706–0.833)

294.5 × 109/L

56.25

90.05

72.97

81.17

Plateletcrit

0.785 (0.721–0.849)

0.275%

70.83

79.10

78.26

67.44

PDW

0.595 (0.528–0.662)

15.9%

54.17

56.22

37.14

71.97

MPV

0.722 (0.661–0.783)

9.3 fl

57.29

75.62

52.88

78.76

PC/MPV

0.801 (0.744–0.858)

31.7

58.33

93.53

81.16

82.46

CRP

0.774 (0.714–0.833)

6.35 mg/L

67.71

82.09

64.36

61.22

ESR

0.848 (0.800–0.896)

17.5 mm/h

72.92

82.59

78.26

67.44

Plasma D-dimer

0.755 (0.696–0.815)

0.92 mg/L

60.42

82.59

62.37

81.37

Plasma fibrinogen

0.807 (0.752–0.862)

3.35 g/L

63.54

84.58

66.30

82.93

  1. WBC, white blood cell count; PC, platelet count; MPV, mean platelet volume; PDW, platelet distribution width; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; AUC, areas under the curve; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value