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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: microRNA-4701-5p protects against interleukin-1β induced human chondrocyte CHON-001 cells injury via modulating HMGA1

Fig. 5

miRNA-4701-5p reduced the apoptosis of IL-1β induced CHON-001 cells by downregulating HMGA1. A, B Flow cytometry analysis of apoptotic cell. C, D Detection of cleaved-caspase3 expression and cleaved-caspase3/GAPDH ratio using western blot assay. **p < 0.01 versus control; ##p < 0.01 versus IL-1β + mimic control; &&p < 0.01 versus IL-1β + miRNA-4701-5p mimic + control-plasmid

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