Skip to main content
Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Cyclic mechanical strain with high-tensile triggers autophagy in growth plate chondrocytes

Fig. 1

CTS treatment significantly increased the mRNA levels of autophagy-related genes in GPCs. Relative expression of LC3, ULK1, ATG5 and BECN1 mRNA determined by RT-qPCR. GAPDH was used as an internal control and served to normalize the results. A–D Chondrocytes were subjected to CTS at different magnitudes for 2 h. E–H Chondrocytes were subjected to CTS at 5500 με for 0.5 h, 2 h and 6 h. Error bars represent standard deviations. n = 3, *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page