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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: LPS-inducible circAtp9b is highly expressed in osteoporosis and promotes the apoptosis of osteoblasts by reducing the formation of mature miR-17-92a

Fig. 4

Analysis of the role of circAtp9b and miR-17-92a in the apoptosis of osteoblasts. Osteoblasts were treated with medium containing 0, 2, 4, 6, 8 and 10 μg/ml LPS was performed for 48 h to achieve LPS treatment, followed by the determination of the expression of circAtp9b (A), premature miR-17-92a (B) and mature miR-17-92a (C). Cell apoptosis assay was performed to explore the role of circAtp9b and miR-17-92a in the apoptosis of osteoblasts (D). CircAtp9b + miR-17-92a, cells co-overexpressed with circAtp9b and mature miR-17-92a. *, p < 0.05

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X