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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: The protective effect of kirenol in osteoarthritis: an in vitro and in vivo study

Fig. 6

Effect of kirenol on OA development in mouse DMM model in vivo. A Typical S–O staining of cartilage and subchondral cortical bone from the different experimental groups at 8 weeks post-surgery (scale bar: 50 µm), and immunohistochemical staining of collagen II, MMP13 expression in the cartilage samples (scale bar: 50 µm). B Diagram showing the OARSI scores of the cartilage. C The percentages of collagen II and MMP13 positive cells in each section were quantified by Image Pro Plus. The data presented are the means ± S.D. *p < 0.05, and **p < 0.01, one-way AVOVA, n = 10 for cartilage OARSI scores, n = 6 for immunohistochemical staining

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