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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Circ_0001174 facilitates osteosarcoma cell proliferation, migration, and invasion by targeting the miR-186-5p/MACC1 axis

Fig. 5

Overexpression of circ_0001174 promotes osteosarcoma (OS) cell proliferation, migration, and invasion. A Circ_0001174 expression level was detected after transfection with overexpression plasmids or negative control in MG63 and HOS cells. B Proliferation activity of oe-circ_0001174 and oe-NC MG63 cells was determined using CCK-8 assay. C Colony formation assay was performed to analyze the proliferation ability of stably transfected MG63 cells. D Transwell migration and invasion assays were used to measure the migration and invasion abilities of stably transfected cells. E Oe-circ_0001174 promoted cell migration capacity in the wound healing assay. *P < 0.05 and **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X