Skip to main content

Table 5 Multivariate Cox analysis of OS and CSS of five types of soft tissue sarcomas with a high risk of lymph node metastasis after propensity score matching (PSM)

From: Risk factors for lymph node metastasis of soft tissue sarcomas of the head, neck, and extremities, and the clinical significance of negative lymph node dissection

Variables

Overall survival

Cancer-specific survival

HR(95%CI)

P

HR(95%CI)

P

Age, years

 < 19

Reference

 

Reference

 

 ≥ 19

3.218 (1.868–5.543)

< 0.001

2.702 (1.49–4.901)

0.001

Year of diagnosis

 1988–2005

Reference

   

 2006–2015

1.089 (0.805–1.472)

0.581

  

Site

 Head, Face, Neck

Reference

 

Reference

 

 Upper limb, shoulder

0.577 (0.3–1.108)

0.099

0.695 (0.324–1.49)

0.35

 Lower limb, hip

0.691 (0.367–1.299)

0.251

0.789 (0.378–1.649)

0.529

Grade

 I + II

Reference

 

Reference

 

 III + IV

1.052 (0.613–1.805)

0.854

1.598 (0.825–3.096)

0.165

 Unknown

1.19 (0.695–2.037)

0.526

1.704 (0.872–3.328)

0.119

Laterality

 Left

    

 Right

1.047 (0.752–1.457)

0.786

1.024 (0.712–1.474)

0.896

 Unknown

0.944 (0.481–1.854)

0.868

1.005 (0.457–2.212)

0.989

Histology

Rhabdomyosarcoma

Reference

 

Reference

 

 Angiosarcoma

0.942 (0.574–1.545)

0.814

1.258 (0.724–2.187)

0.415

 Ewing sarcoma

0.397 (0.187–0.845)

0.02

0.53 (0.236–1.187)

0.123

 Epithelioid sarcoma

0.692 (0.415–1.154)

0.158

0.825 (0.464–1.466)

0.512

 Clear cell sarcoma

0.785 (0.455–1.355)

0.385

1.08 (0.593–1.969)

0.801

Stage

 Localized

Reference

 

Reference

 

 Regional

1.501 (1.078–2.09)

0.02

1.689 (1.181–2.415)

0.004

 Distant

3.336 (1.776–6.266)

< 0.001

4.308 (2.259–8.217)

< 0.001

NLND

 No

Reference

 

Reference

 

 Yes

0.718 (0.535–0.962)

0.03

0.699 (0.506–0.967)

0.031

Size, cm

 < 4

Reference

 

Reference

 

 4–10

1.816 (1.26–2.616)

0

2.3 (1.513–3.496)

< 0.001

 ≥ 10

2.708 (1.636–4.482)

< 0.001

3.266 (1.857–5.745)

< 0.001

Marital status

 Married

Reference

 

Reference

 

 Never married

0.949 (0.633–1.422)

0.799

0.976 (0.627–1.52)

0.915

 Divorced/widowed/separated

1.971 (1.279–3.037)

0

1.832 (1.13–2.972)

0.014

 Unknown

1.077 (0.465–2.491)

0.863

1.046 (0.39–2.804)

0.929

  1. The values in bold indicate that the p value < 0.05, and the results are statistically significant