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Table 4 Clinical characteristics of five types of soft tissue sarcomas with a high risk of lymph node metastasis, before and after propensity score matching (PSM)

From: Risk factors for lymph node metastasis of soft tissue sarcomas of the head, neck, and extremities, and the clinical significance of negative lymph node dissection

Variables

Lymph node treatment group in raw data

Lymph node treatment group after PSM

Non-NLND (n = 968)

NLND (n = 260)

P value

Non-NLND (n = 244)

NLND (n = 244)

P value

Age, median (IQR)

46.0 [22.0;68.0]

26.0 [12.0;47.2]

< 0.001

34.5 [13.0;57.2]

29.0 [12.0;48.2]

0.017

Age, years

  

< 0.001

  

0.703

 < 19

196 (20.2%)

97 (37.3%)

 

81 (33.2%)

86 (35.2%)

 

 ≥ 19

772 (79.8%)

163 (62.7%)

 

163 (66.8%)

158 (64.8%)

 

Race

  

0.468

  

0.039

 White

772 (79.8%)

215 (82.7%)

 

180 (73.8%)

203 (83.2%)

 

 Black

107 (11.1%)

27 (10.4%)

 

36 (14.8%)

24 (9.84%)

 

 Other

89 (9.19%)

18 (6.92%)

 

28 (11.5%)

17 (6.97%)

 

Sex

  

0.173

  

0.069

 Female

421 (43.5%)

126 (48.5%)

 

99 (40.6%)

120 (49.2%)

 

 Male

547 (56.5%)

134 (51.5%)

 

145 (59.4%)

124 (50.8%)

 

Year of diagnosis

  

0.231

  

1

 1988–2005

364 (37.6%)

109 (41.9%)

 

105 (43.0%)

105 (43.0%)

 

 2006–2015

604 (62.4%)

151 (58.1%)

 

139 (57.0%)

139 (57.0%)

 

Site

  

< 0.001

  

0.711

 Head, Face, Neck

260 (26.9%)

52 (20.0%)

 

59 (24.2%)

52 (21.3%)

 

 Upper limb, shoulder

200 (20.7%)

97 (37.3%)

 

87 (35.7%)

87 (35.7%)

 

 Lower limb, hip

508 (52.5%)

111 (42.7%)

 

98 (40.2%)

105 (43.0%)

 

Grade

  

0.127

  

0.899

 I + II

114 (11.8%)

25 (9.62%)

 

22 (9.02%)

25 (10.2%)

 

 III + IV

408 (42.1%)

97 (37.3%)

 

94 (38.5%)

93 (38.1%)

 

 Unknown

446 (46.1%)

138 (53.1%)

 

128 (52.5%)

126 (51.6%)

 

Laterality

  

0.022

  

0.9

 Left

364 (37.6%)

119 (45.8%)

 

111 (45.5%)

106 (43.4%)

 

 Right

399 (41.2%)

102 (39.2%)

 

95 (38.9%)

99 (40.6%)

 

 Unknown

205 (21.2%)

39 (15.0%)

 

38 (15.6%)

39 (16.0%)

 

Histology

  

< 0.001

  

0.949

 Rhabdomyosarcoma

255 (26.3%)

78 (30.0%)

 

73 (29.9%)

78 (32.0%)

 

 Angiosarcoma

344 (35.5%)

42 (16.2%)

 

44 (18.0%)

42 (17.2%)

 

 Ewing sarcoma

184 (19.0%)

19 (7.31%)

 

18 (7.38%)

19 (7.79%)

 

 Epithelioid sarcoma

109 (11.3%)

75 (28.8%)

 

69 (28.3%)

62 (25.4%)

 

 Clear cell sarcoma

76 (7.85%)

46 (17.7%)

 

40 (16.4%)

43 (17.6%)

 

Stage

  

0.05

  

0.661

 Localized

663 (68.5%)

171 (65.8%)

 

169 (69.3%)

160 (65.6%)

 

 Regional

238 (24.6%)

79 (30.4%)

 

65 (26.6%)

74 (30.3%)

 

 Distant

67 (6.92%)

10 (3.85%)

 

10 (4.10%)

10 (4.10%)

 

Size, cm

  

0.006

  

0.597

 < 4

368 (38.0%)

121 (46.5%)

 

109 (44.7%)

114 (46.7%)

 

 4–10

407 (42.0%)

107 (41.2%)

 

109 (44.7%)

99 (40.6%)

 

 ≥ 10

193 (19.9%)

32 (12.3%)

 

26 (10.7%)

31 (12.7%)

 

Marita status

  

< 0.001

  

0.858

 Married

407 (42.0%)

70 (26.9%)

 

76 (31.1%)

69 (28.3%)

 

 Never married

404 (41.7%)

152 (58.5%)

 

134 (54.9%)

139 (57.0%)

 

 Divorced/Widowed/Separated

138 (14.3%)

29 (11.2%)

 

29 (11.9%)

29 (11.9%)

 

 Unknown

19 (1.96%)

9 (3.46%)

 

5 (2.05%)

7 (2.87%)

 

Survival months (median, IQR)

47.0 [17.0;108]

69.0 [26.8;136]

< 0.001

57.5 [21.0;120]

69.5 [26.8;136]

0.08

  1. NLND negative lymph node dissection
  2. The values in bold indicate that the p value < 0.05, and the results are statistically significant