Table 1 Characteristics of enrolled patients divided into lymph node-negative and node-positive groups
Characteristics | Total | Negative | Positive | p valuea |
|---|---|---|---|---|
N (%) | 3276 | 2993 (91.4%) | 283 (8.64%) | |
Age, median (IQRb) | 53.0 [31.0;69.0] | 54.0 [35.0;70.0] | 24.0 [10.0;51.0] | < 0.001 |
Age, years (%) | < 0.001 | |||
< 19 | 537 (16.4%) | 411 (13.7%) | 126 (44.5%) | |
≥ 19 | 2739 (83.6%) | 2582 (86.3%) | 157 (55.5%) | |
Race (%) | 0.002 | |||
White | 2700 (82.4%) | 2487 (83.1%) | 213 (75.3%) | |
Black | 338 (10.3%) | 293 (9.79%) | 45 (15.9%) | |
Otherc | 238 (7.26%) | 213 (7.12%) | 25 (8.83%) | |
Sex (%) | 0.055 | |||
Female | 1398 (42.7%) | 1293 (43.2%) | 105 (37.1%) | |
Male | 1878 (57.3%) | 1700 (56.8%) | 178 (62.9%) | |
Year of diagnosis (%) | 0.664 | |||
1988–2005 | 1286 (39.3%) | 1171 (39.1%) | 115 (40.6%) | |
2006–2015 | 1990 (60.7%) | 1822 (60.9%) | 168 (59.4%) | |
Site (%) | < 0.001 | |||
Head, Face, Neck | 676 (20.6%) | 581 (19.4%) | 95 (33.6%) | |
Upper limb, shoulder | 820 (25.0%) | 744 (24.9%) | 76 (26.9%) | |
Lower limb, hip | 1780 (54.3%) | 1668 (55.7%) | 112 (39.6%) | |
Grade (%) | < 0.001 | |||
I + II | 687 (21.0%) | 680 (22.7%) | 7 (2.47%) | |
III + IV | 1325 (40.4%) | 1216 (40.6%) | 109 (38.5%) | |
Unknown | 1264 (38.6%) | 1097 (36.7%) | 167 (59.0%) | |
Laterality (%) | < 0.001 | |||
Left | 1382 (42.2%) | 1285 (42.9%) | 97 (34.3%) | |
Right | 1372 (41.9%) | 1255 (41.9%) | 117 (41.3%) | |
Unknown | 522 (15.9%) | 453 (15.1%) | 69 (24.4%) | |
Histology (%) | < 0.001 | |||
Leiomyosarcoma | 1598 (48.8%) | 1577 (52.7%) | 21 (7.42%) | |
Rhabdomyosarcoma | 581 (17.7%) | 434 (14.5%) | 147 (51.9%) | |
Angiosarcoma | 469 (14.3%) | 431 (14.4%) | 38 (13.4%) | |
Ewing sarcoma | 262 (8.00%) | 237 (7.92%) | 25 (8.83%) | |
Epithelioid sarcoma | 217 (6.62%) | 190 (6.35%) | 27 (9.54%) | |
Clear cell sarcoma | 149 (4.55%) | 124 (4.14%) | 25 (8.83%) | |
Stage (%) | < 0.001 | |||
Localized | 2177 (66.5%) | 2177 (72.7%) | 0 (0.00%) | |
Regional | 820 (25.0%) | 636 (21.2%) | 184 (65.0%) | |
Distant | 279 (8.52%) | 180 (6.01%) | 99 (35.0%) | |
Surgery (%) | < 0.001 | |||
No | 331 (10.1%) | 237 (7.92%) | 94 (33.2%) | |
Yes | 2945 (89.9%) | 2756 (92.1%) | 189 (66.8%) | |
Lymph nodes dissection (%) | < 0.001 | |||
No | 2738 (83.6%) | 2615 (87.4%) | 123 (43.5%) | |
Yes | 538 (16.4%) | 378 (12.6%) | 160 (56.5%) | |
Size, cm (%) | < 0.001 | |||
< 4 | 1362 (41.6%) | 1297 (43.3%) | 65 (23.0%) | |
4–10 | 1300 (39.7%) | 1163 (38.9%) | 137 (48.4%) | |
≥ 10 | 614 (18.7%) | 533 (17.8%) | 81 (28.6%) | |
Marital status (%) | < 0.001 | |||
Married | 1531 (46.7%) | 1455 (48.6%) | 76 (26.9%) | |
Never married | 1123 (34.3%) | 939 (31.4%) | 184 (65.0%) | |
Divorced/Widowed/Separated | 503 (15.4%) | 484 (16.2%) | 19 (6.71%) | |
Unknown | 119 (3.63%) | 115 (3.84%) | 4 (1.41%) | |
Survival months, median (IQR) | 52.0 [21.0;110] | 55.0 [22.0;112] | 23.0 [11.5;74.5] | < 0.001 |