Fig. 3

CD44 knockdown inhibited the proliferation of MG63 and U2OS cells. A CCK8 assay demonstrated that silencing of CD44 inhibited the cell proliferation capability on the indicated time points after transfection with CD44 siRNA (si-CD44). *P < 0.05, **P < 0.01 versus si-NC group (the significant differences between the si-CD44-1, si-CD44-2 group and the si-NC group were consistent, with a common label). B Colony formation in MG-63 and U2OS cells. All data are presented as the mean ± SD of n = 3 experiments