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Table 1 The characteristics of the included studies

From: The Effect of Intra-articular Injection of Hyaluronic Acid in Frozen Shoulder: a Systematic Review and Meta-analysis of Randomized Controlled Trials

References

Group

Number

Side (right/left)

Age

Gender (male/total)

Dose

Outcome

Follow ups

Akhtar et al. [25]

HA, NSAIDS

80, 80

92/68

45.37 ± 5.743, 37.87 ± 1.027

74/160

40 mg, once

UCLA

4 weeks

Lim et al. [26]

HA, corticosteroid

34, 34

36/30

53.8 (range 37–77 years)

19/68

20 mg, 3 times

VAS, ASES, Constant, ROM

2, 12 weeks

Park et al. [27]

HA + distension, corticosteroid

45, 45

64/26

56.33 ± 5.92, 55.23 ± 4.69

22/90

20 mg, 3 times

SPADI, VNS, ROM

2, 6, 12 weeks

Hsieh et al. [28]

HA + PT,PT

32, 31

 

52.6 ± 6.3, 56.4 ± 9

20/63

20 mg, 3 times

SPADI, ROM, SDQ, SF36

1.5, 3 months

Calis et al. [29]

HA, triamsinolone, PT, Stretching

10, 9, 8, 6

52/46

59.7 ± 9.81, 56.36 ± 11.3, 52.33 ± 10.1, 59.25 ± 6.8

33/90

30 mg, 2 times

VAS, ROM, Constant

15 days, 3 months

Rovetta and Montefote [15]

HA + steroid, PT + steroid

16, 14

18/14

65.8 ± 9.1, 62.3 ± 13

9/30

20 mg, 9 times

ROM,VAS

6 months

Oh et al. [30]

CS, HA, CS + HA, Saline

15, 15, 15, 15

 

52.3 ± 8.5, 54.5 ± 5.1, 53.5 ± 7.5, 49.4 ± 4.9

21/60

2 mL, once

ROM, VAS, UCLA, ASES, Constant, SPADI

1 week and 1, 3, 6 months

  1. HA, hyaluronic acid; NSAIDS, non-steroidal anti-inflammatory drugs; UCLA, University of California Los-Angeles; VAS, visual analog scale; ASES, American Shoulder and Elbow Surgeon; ROM, range of motion; SPADI, Shoulder Pain and Disability Index; VNS, Verbal Numeric Scale; PT, physical therapy; SDQ, Shoulder Disability Questionnaire; SF36, Medical Outcomes Study 36-Item Short-Form Health Survey