Fig. 1

The therapeutic effect of GA on rheumatoid arthritis. A 2D structure of gentisic acid. B Representative picture of joint swelling in CIA rats. C The effect of GA on serum RF levels. D The effect of GA on serum IFN-γ IL-1β, TNF-α, IL-4, and IL-10 levels. Arthritis index: 0 means no redness and swelling; 1 means little toe joints are slightly swollen and red; 2 means more than one joint is swollen and red; 3 means toe joints and feet are swollen; 4 means ankle joints and feet below the ankle joints The paws are swollen. *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the control group. ^$P < 0.05, ^$$P < 0.01, and ^$$$P < 0.001 compared with model group