Fig. 6

miR-589-3p directly target to ATF1 3′UTR. A Putative binding sites between miR-589-3p and ATF1; B Luciferase reporter assay showed that miR-589-3p mimic transfection suppressed the relative luciferase activity of the ATF1-Wt reporter in PGLSCs; C Relative ATF1 expression in inhibitor NC, miR-589-3p inhibitor, mimic NC and miR-589-3p mimic groups. *P < 0.05