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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Circ_0043947 contributes to interleukin 1β-induced injury in chondrocytes by sponging miR-671-5p to up-regulate RTN3 expression in osteoarthritis pathology

Fig. 1

IL-1β up-regulates circ_0043947 expression in chondrocytes. A Circ_0043947 (393 nt) was derived from the back-splicing of exon 18–23 of BRCA1 gene. B The circular structure of circ_0043947 was tested by RNase R, and linear BRCA1 mRNA acted as the control. C The stability of circ_0043947 was examined by Act D, and linear BRCA1 mRNA served as the control. D The expression of circ_0043947 in IL-1β-induced chondrocytes (10 ng/mL, 24 h) was determined by RT-qPCR. *P < 0.05, ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X