Fig. 6

LncRNA LINC00662 regulates cell proliferation, migration and invasion via mediating miR-30b-3p/ELK1 axis. A Relative expression of ELK1 was detected by qRT-PCR. **P < 0.01, versus hFOB. B Relative expression of ELK1 was detected by qRT-PCR after transfection with pcDNA-ELK1. **P < 0.01, versus pcDNA-NC. C The cell viability was determined by MTT assay in MG63 cells. *P < 0.05, **P < 0.01, versus sh-NC. ^#P < 0.05, versus sh-LINC00662. D Wound healing rate of cells was determined by wound healing assay in MG63 cells. *P < 0.05, **P < 0.01, versus sh-NC. ^#P < 0.05, versus sh-LINC00662. Scale bar = 100 µm. E Relative number of invasion cells in MG63 cells was detected by transwell assay. *P < 0.05, **P < 0.01, versus sh-NC. ^#P < 0.05, versus sh-LINC00662. Scale bar = 100 µm