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Table 3 Comparison of intraoperative blood loss and hematological indicators at the end of surgery among study groups

From: Acute normovolemic hemodilution in combination with tranexamic acid is an effective strategy for blood management in lumbar spinal fusion surgery

Intraoperative variables ANH TXA ANH + TXA Control Overall P value
Blood loss, mL 545.32 ± 189.29 378.72 ± 96.57ab 336.16 ± 88.46ab 578.44 ± 201.81 < 0.001
Hemoglobin, g/dL (at the end of surgery) 12.07 ± 1.21 11.69 ± 1.37 11.94 ± 1.71 11.26 ± 1.26 0.195
PCV (at the end of surgery) 33.41 ± 4.12 32.67 ± 3.43 33.80 ± 4.89 31.98 ± 4.27 0.282
Hemoglobin, g/dL (at the postoperative first day) 10.13 ± 1.24a 9.98 ± 1.31a 11.07 ± 1.41abc 8.63 ± 1.63 0.154
PCV (at the postoperative first day) 30.98 ± 3.27a 31.89 ± 3.48a 33.68 ± 4.09abc 29.02 ± 3.06 0.161
  1. Letter “a” indicated P < 0.05 compared with control group, letter “b” indicated P < 0.05 compared with ANH group, letter “c” indicated P < 0.05 compared with TXA group, respectively
  2. ANH Acute normovolemic hemodilution, TXA Tranexamic acid, PCV packed cell volume