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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Circ_0001947 promotes cell proliferation, invasion, migration and inflammation and inhibits apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes through miR-671-5p/STAT3 axis

Fig. 3

MiR-671-5p was the target of circ_0001947. A The binding sites between circ_0001947 and miR-671-5p. B The expression of miR-671-5p in RA-FLSs transfected with miR-NC or miR-671-5p was detected by qRT-PCR. C The relationship between circ_0001947 and miR-671-5p was demonstrated by dual-luciferase reporter assay. D The expression of miR-671-5p in RA patients and normal controls was determined by qRT-PCR. E The correlation between the levels of circ_0001947 and miR-671-5p in RA patients was analyzed. F The expression of miR-671-5p in RA-FLSs and normal FLSs was detected by qRT-PCR. G The expression of circ_0001947 in RA-FLSs transfected with pCD5-ciR or circ_0001947 was examined via qRT-PCR. H The expression of miR-671-5p in RA-FLSs transfected with si-NC, si-circ_0001947, pCD5-ciR or circ_0001947 was detected by qRT-PCR. **P < 0.01, ****P < 0.0001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X