Table 2 Comparison of the genotype and allele frequency between the patients and controls
Genotype | P | Allele | P | Odds ratio (95% CIa) | |||||
|---|---|---|---|---|---|---|---|---|---|
XX | Xx | xx | X | x | |||||
rs148363003 | Patients (n = 600) | 489 (81.5%) | 84 (14.0%) | 27 (4.5%) | 0.004 | 1062 (88.5%) | 138 (11.5%) | 0.002 | 1.49 (1.16–1.92) |
Controls (n = 800) | 679 (84.9%) | 114 (14.2%) | 7 (0.9%) | 1472 (92.0%) | 128 (8.0%) | ||||
rs117605225 | Patients (n = 600) | 570 (95.0%) | 26 (4.3%) | 4 (0.7%) | 0.54 | 1166 (97.2%) | 34 (2.8%) | 0.52 | 0.87 (0.56–1.34) |
Controls (n = 800) | 750 (93.8%) | 48 (6.0%) | 2 (0.2%) | 1548 (96.7%) | 52 (3.3%) | ||||
rs360136 | Patients (n = 600) | 180 (30.0%) | 291 (48.5%) | 129 (21.5%) | 0.92 | 652 (54.3%) | 548 (46.7%) | 0.95 | 1.01 (0.86–1.16) |
Controls (n = 800) | 234 (29.2%) | 403 (50.4%) | 163 (20.4%) | 871 (54.4%) | 729 (46.6%) | ||||
rs111597524 | Patients (n = 600) | 301 (50.2%) | 280 (46.6%) | 19 (3.2%) | 0.71 | 882 (73.4%) | 318 (26.6%) | 0.74 | 0.97 (0.82–1.15) |
Controls (n = 800) | 388 (48.5%) | 391 (48.9%) | 21 (2.6%) | 1167 (72.9%) | 433 (27.1%) | ||||
rs194757 | Patients (n = 600) | 284 (47.4%) | 256 (42.6%) | 60 (10.0%) | 0.18 | 824 (68.7%) | 376 (31.3%) | 0.22 | 0.91 (0.77–1.06) |
Controls (n = 800) | 351 (43.9%) | 362 (45.3%) | 87 (10.9%) | 1064 (66.5%) | 536 (33.5%) | ||||
rs1547233 | Patients (n = 600) | 332 (55.3%) | 244 (40.8%) | 24 (4.0%) | 0.20 | 908 (75.6%) | 292 (24.4%) | 0.37 | 0.92 (0.78–1.09) |
Controls (n = 800) | 423 (52.9%) | 332 (41.5%) | 45 (5.6%) | 1187 (73.7%) | 413 (26.4%) | ||||