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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: miR-653-5p suppresses the viability and migration of fibroblast-like synoviocytes by targeting FGF2 and inactivation of the Wnt/beta-catenin pathway

Fig. 4

FGF2 deletion suppresses RA development. A RT-qPCR was used to determine FGF2 expression in HFLS-RA cells transfected with shFGF2 or shNC. B–D MTT, wound healing, and transwell assays showed cell viability, migration, and invasion in HFLS-RA cells transfection of shFGF2 or shNC. E and F Western blot and RT-qPCR assays showed the protein and mRNA expression of Rac1, Cdc42, and RhoA in HFLS-RA cells transfected with shFGF2 or shNC. **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X