Fig. 3

Macroscopic pathology of implanted knees. Macroscopic changes in implanted knees at day 28 following surgery in animals that received an IA bolus of TXA or ALM. a Representative images of a native knee and implanted knees from TXA- and ALM-treated animals. External views of the knee joints after removal of the skin (upper panels). Posterior (second row) and internal (third row) view of the joints following dissection of the patella (lower panels). b Differences in the extension range of motion (ROM) for native and implanted knees tended to be greater for TXA- compared to ALM-treated animals. c Compared to native knees, the circumference of implanted knees was increased for TXA- and ALM-treated animals. d Macroscopic pathology scores tended to be lower for ALM- than TXA-treated knees. Data show mean ± SEM