Fig. 8

Rg3 treatment inhibited OS cell malignancy in vivo. A–C The effect of Rg3 treatment on tumorigenesis of MG63 cells. D–F The impacts of Rg3 treatment on the expression of circ_0003074, miR-516b-5p and KPNA4 were determined by qRT-PCR or Western blotting in the primary tumors from MG63 cells. G The positive expression rate of Ki-67 was checked by IHC assay in the primary tumors from MG63 cells. **P < 0.01 and ***P < 0.001