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Fig. 8 | Journal of Orthopaedic Surgery and Research

Fig. 8

From: Down-regulation of circ_0058058 suppresses proliferation, angiogenesis and metastasis in multiple myeloma through miR-338-3p/ATG14 pathway

Fig. 8

Knockdown of circ_0058058 inhibits MM growth in xenograft murine models. A The volume of MM tumors was detected every week after treatment for 7 days. B Typical MM tumors after subcutaneous injection of H929 cells stably knockdown circ_0058058. C The weight of MM tumors was detected after treatment for 28 days. D–G RT-qPCR and Western blot analysis of circ_0058058, miR-338-3p and ATG14 expression in xenograft of each group. H IHC staining for ki67 protein level in xenograft of each group. *P < 0.05

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