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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Discoidin domain receptor 2 activation of p38 mitogen-activated protein kinase as an important pathway for osteonectin-regulating osteoblast mineralization

Fig. 1

Osteonectin enhanced the gene expressions of COL1 and DDR2. The mRNA expressions of COL1a1, COL1a2 and DDR2 were quantified by RT-qPCR; **P < .01, ***P < .001 versus the CON group; the experiments were conducted in triplicates; data were expressed by means ± standard deviation (SD). COL1: collagen 1; DDR2: discoidin domain receptor 2; RT-qPCR: reverse transcription-quantitative polymerase chain reaction; CON group: control group, the osteoblasts were added with mineralized solution; ON group: osteonectin group, the osteoblasts were added with mineralized solution + 1 µg/mL osteonectin

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