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Table 1 Effect of RDTF and CaCO3 on the trabecular microstructure of OVX rats

From: Rhizoma drynariae total flavonoids combined with calcium carbonate ameliorates bone loss in experimentally induced Osteoporosis in rats via the regulation of Wnt3a/β-catenin pathway

Parameters

Sham

OVX

CaCO3

RDTF

RDTF + CaCO3

 

BMD (g/cm2)

0.258 ± 0.004

0.189 ± 0.005***

0.236 ± 0.009**###

0.233 ± 0.014**###

0.248 ± 0.003###

 

BMC (g/cm2)

0.087 ± 0.001

0.070 ± 0.002***

0.074 ± 0.003***#

0.073 ± 0.001***&

0.077 ± 0.001***###

 

BV/TV (%)

0.502 ± 0.019

0.287 ± 0.026***

0.399 ± 0.021***###&

0.415 ± 0.009***###

0.445 ± 0.007**###

 

Tb.Th (mm)

0.122 ± 0.025

0.072 ± 0.015***

0.085 ± 0.009**

0.120 ± 0.014#

0.122 ± 0.010###

 

Tb.Sp (mm)

0.141 ± 0.012

0.173 ± 0.008**

0.170 ± 0.011**&

0.152 ± 0.003#

0.145 ± 0.008##

 
  1. BMD: bone mineral density; BMC: bone mineral content; BV/TV: bone volume/tissue volume; Tb.Th: trabecular thickness; Tb.Sp: trabecular separation
  2. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Sham. #P < 0.05, ##P < 0.01, ###P < 0.001 vs. OVX. &P < 0.05 vs RDTF + CaCO3