Table 1 Demographic characteristics of infused and non infused human albumin
Infused human albumin | P | ||
|---|---|---|---|
No (N = 2226) | Yes (N = 256) | ||
Age (%) | < 0.001 | ||
< 55 | 344 (15.5) | 36 (14.1) | |
55–75 | 1606 (72.1) | 143 (55.9) | |
> 75 | 276 (12.4) | 77 (30.1) | |
Sex (%) | 0.572 | ||
Male | 1084 (48.7) | 130 (50.8) | |
Female | 1142 (51.3) | 126 (49.2) | |
BMI (mean (SD)) | 25.69 (3.58) | 25.05 (4.20) | 0.008 |
Previous history (%) | |||
Surgery | 484 (21.7) | 48 (18.8) | 0.305 |
Blood transfusion | 58 (2.6) | 6 (2.3) | 0.966 |
Allergies | 41 (1.8) | 5 (2.0) | 0.905 |
Smoking | 376 (16.9) | 38 (14.8) | 0.457 |
Alcohol consumption | 326 (14.6) | 31 (12.1) | 0.317 |
Comorbidities (%) | |||
Hypertension | 754 (33.9) | 98 (38.3) | 0.181 |
T2DM | 438 (19.7) | 77 (30.1) | < 0.001 |
Coronary heart disease | 313 (14.1) | 37 (14.5) | 0.940 |
Cerebral thrombosis | 18 (0.8) | 5 (2.0) | 0.143 |
Respiratory diseases | 123 (5.5) | 15 (5.9) | 0.939 |
Digestive system diseases | 212 (9.5) | 38 (14.8) | 0.010 |
Other | 294 (13.2) | 33 (12.9) | 0.965 |
Laboratory tests (median [IQR]) | |||
TP | 75.11 [65.80, 100.00] | 81.44 [65.86, 100.00] | 0.804 |
GLO | 24.90 [22.20, 27.37] | 25.26 [22.58, 27.45] | 0.364 |
ALB | 36.51 [31.40, 46.70] | 28.56 [21.23, 36.85] | < 0.001 |
ALB/GLO | 1.44 [1.14, 1.79] | 1.04 [0.73, 1.41] | < 0.001 |
TBIL | 13.10 [9.91, 17.30] | 13.27 [9.80, 17.11] | 0.544 |
DBIL | 3.63 [2.66, 5.00] | 3.70 [2.50, 5.00] | 0.800 |
IBIL | 9.48 [7.05, 12.41] | 9.30 [7.04, 12.00] | 0.497 |
ALT | 18.70 [14.00, 28.00] | 19.00 [15.07, 28.00] | 0.134 |
AST | 17.30 [14.40, 22.00] | 18.00 [15.00, 22.12] | 0.249 |
ALT/AST | 1.10 [0.86, 1.42] | 1.10 [0.83, 1.40] | 0.466 |
PA | 219.00 [176.00, 262.00] | 204.65 [165.62, 251.40] | 0.005 |
Operation (median [IQR]) | |||
Bleeding volume | 400.00 [400.00, 550.00] | 400.00 [400.00, 600.00] | 0.001 |
Surgery time | 140.00 [100.00, 200.00] | 157.50 [115.00, 210.00] | 0.005 |
Indications for surgery (%) | |||
LDH | 1294 (58.1) | 145 (56.6) | 0.575 |
LSS | 803 (36.1) | 92 (35.9) | |
Lumbar spondylolisthesis | 129 (5.8) | 19 (7.4) | |
Fusion segment (%) | |||
1 | 1024 (46.0) | 97 (37.9) | < 0.001 |
2 | 881 (39.6) | 92 (35.9) | |
≥ 3 | 321 (14.4) | 67 (26.2) | |