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Table 4 Estimated hazard ratios of selected covariates for overall mortality in nonagenarian hip surgery patients

From: Factors influencing early and long-term survival following hip fracture among nonagenarians

 

No. of complications

Severity of complications

Hazard ratio

p value

Hazard ratio

p value

Sex

1.4 (0.9–2.2)

0.197

1.5 (0.9–2.4)

0.095

Frailty

1.5 (0.8–2.6)

0.174

1.4 (0.8–2.5)

0.241

Weight

1.0 (1.0–1.0)

0.791

1.0 (1.0–1.0)

0.490

ASA classification

1.3 (0.5–3.4)

0.534

1.2 (0.5–3.0)

0.731

Congestive heart failure

1.8 (1.2–2.8)

0.008*

1.7 (1.1–2.7)

0.027

Charlson comorbidity index

1.0 (0.9–1.2)

0.640

1.0 (0.9–1.2)

0.524

Time to surgery

1.0 (1.0–1.0)

0.391

1.0 (1.0–1.0)

0.154

Surgery performed out-of-hours

1.5 (1.0–2.2)

0.084

1.7 (1.1–2.6)

0.017*

Hypertensive response immediately before anaesthesia induction

1.7 (0.9–3.3)

0.093

1.1 (0.5–2.3)

0.773

Combined regional anaesthesia

1.1 (0.7–1.7)

0.557

1.2 (0.8–1.9)

0.378

Number of intraoperative hypotensive episodes

0.9 (0.8–1.0)

0.039

0.9 (0.8–1.0)

0.116

Intraoperative opioid dose

1.0 (1.0–1.0)

0.119

1.0 (1.0–1.0)

0.206

Postoperative opioid dose

 Day of admission to 12 days

1.0 (1.0–1.0)

0.265

1.0 (1.0–1.0)

0.006*

 After 12 days

1.0 (1.0–1.0)

0.005*

No. of medical emergency team activations

1.0 (0.8–1.3)

0.802

0.9 (0.7–1.2)

0.609

Number of complications

1.3 (1.1–1.5)

0.003*

Clavien Dindo severity

 Day of admission to 12 days

3.0 (2.4–3.6)

< 0.001*

 12 days to 7 months

1.2 (0.9–1.6)

0.145

 After 7 months

1.0 (0.6–1.6)

0.982

  1. Hazard ratios are estimated using constant proportional hazard ratio assumption validated Cox regression for number of complications and time-dependent coefficient Cox regression for severity of complications. Estimated hazard ratios are presented with 95% CI
  2. *Two-sided p value below 0.025, a Bonferroni’s corrected significance level