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Table 3 Association between serum estradiol level (pg/mL) and lumbar bone mineral density (mg/cm2)

From: Association between serum estradiol level, sex hormone binding globulin level, and bone mineral density in middle-aged postmenopausal women

 

Model 1

β (95% CI)

Model 2

β (95% CI)

Model 3

β (95% CI)

Serum estradiol level

0.80 (0.54, 1.06)***

0.71 (0.44, 0.98)***

0.65 (0.38, 0.93)***

Serum estradiol level categories

Q1

Reference

Reference

Reference

Q2

28.09 (− 4.47, 60.66)

22.62 (− 9.46, 54.70)

9.48 (− 23.99, 42.96)

Q3

58.25 (25.96, 90.53)

53.09 (21.27, 84.92)

36.44 (1.96, 70.93)

Q4

115.57 (84.12, 147.02)

107.49 (75.11, 139.86)

90.98 (55.80, 126.16)

P for trend

 < 0.001

 < 0.001

 < 0.001

  1. Model 1: no covariates were adjusted. Model 2: age, and race were adjusted. Model 3: age, race, educational level, body mass index, ratio of family income to poverty, moderate activities, smoked at least 100 cigarettes in life, had at least 12 alcohol drinks in a year, blood urea nitrogen, serum uric acid, serum phosphorus, and serum calcium were adjusted
  2. *P < 0.05; **P < 0.01; ***P < 0.001