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Table 2 Weighted characteristics of study population based on sex hormone binding globulin quartiles

From: Association between serum estradiol level, sex hormone binding globulin level, and bone mineral density in middle-aged postmenopausal women

Sex hormone binding globulin level (nmol/L)

Q1

(≤ 35.96)

Q2

(35.97–52.0)

Q3

(52.08–75.52)

Q4

(≥ 76.23)

P value

Age (years)

51.9 ± 5.0

53.0 ± 5.0

52.8 ± 4.6

52.9 ± 4.5

0.200

Race/Ethnicity (%)

0.008

Non-Hispanic White

67.8

58.4

62.6

79.5

 

Non-Hispanic Black

10.0

16.4

13.5

9.4

 

Mexican American

8.9

11.8

8.0

3.7

 

Other race/ethnicity

13.3

13.5

15.9

7.3

 

Education level (%)

0.006

Less than high school

10.5

16.4

18.2

11.0

 

High school

30.4

27.9

20.9

16.1

 

More than high school

59.1

55.7

60.9

72.9

 

Body mass index (kg/m2)

34.6 ± 7.0

31.5 ± 6.4

30.4 ± 7.3

27.2 ± 6.0

 < 0.001

Income to poverty ratio

3.0 ± 1.5

3.1 ± 1.6

3.3 ± 1.8

3.2 ± 1.7

0.309

Moderate activities (%)

0.099

Yes

39.9

45.6

40.4

51.9

 

No

60.1

54.4

59.6

48.1

 

Smoked at least 100 cigarettes in life (%)

0.116

Yes

41.6

42.8

34.5

47.6

 

No

58.4

57.2

65.5

52.4

 

Had at least 12 alcohol drinks in a year (%)

 < 0.001

Yes

57.5

75.9

62.5

83.2

 

No

42.5

24.1

37.5

16.8

 

Blood urea nitrogen (mg/dL)

5.1 ± 1.6

4.9 ± 1.5

4.7 ± 1.6

4.9 ± 1.7

0.107

Serum uric acid (umol/L)

324.0 ± 64.1

301.5 ± 68.3

285.1 ± 62.8

260.8 ± 65.2

 < 0.001

Serum phosphorus (mg/dL)

1.2 ± 0.2

1.2 ± 0.2

1.2 ± 0.2

1.3 ± 0.1

0.035

Serum calcium (mg/dL)

2.4 ± 0.1

2.4 ± 0.1

2.4 ± 0.1

2.4 ± 0.1

0.517

Serum estradiol level (pg/mL)

23.6 ± 37.7

17.8 ± 37.2

27.1 ± 45.9

28.6 ± 48.2

0.140

Lumbar bone mineral density (mg/cm2)

1011.6 ± 137.4

998.2 ± 156.4

962.9 ± 140.6

991.4 ± 142.6

0.032

  1. Mean ± SD for continuous variables: P value was calculated by weighted linear regression model. % for Categorical variables: P value was calculated by weighted chi-square test