Table 1 Weighted characteristics of study population based on serum estradiol level quartiles
Serum estradiol level (pg/mL) | Q1 (≤ 4.04) | Q2 (4.08–7.58) | Q3 (7.59–16.10) | Q4 (≥ 16.30) | P value |
|---|---|---|---|---|---|
Age (years) | 54.0 ± 4.3 | 53.8 ± 4.1 | 53.2 ± 4.4 | 50.2 ± 5.0 | < 0.001 |
Race/Ethnicity (%) | 0.631 | ||||
Non-Hispanic White | 61.4 | 69.9 | 68.9 | 70.4 | |
Non-Hispanic Black | 11.3 | 12.8 | 12.1 | 12.1 | |
Mexican American | 10.1 | 8.3 | 7.5 | 5.8 | |
Other race/ethnicity | 17.1 | 9.0 | 11.5 | 11.7 | |
Education level (%) | 0.018 | ||||
Less than high school | 18.3 | 16.0 | 12.2 | 10.0 | |
High school | 27.3 | 16.1 | 29.3 | 20.9 | |
More than high school | 54.4 | 67.9 | 58.5 | 69.1 | |
Body mass index (kg/m2) | 26.4 ± 5.6 | 29.9 ± 5.8 | 33.4 ± 6.1 | 32.2 ± 8.5 | < 0.001 |
Income to poverty ratio | 2.9 ± 1.8 | 3.2 ± 1.7 | 3.2 ± 1.5 | 3.4 ± 1.6 | 0.096 |
Moderate activities (%) | 0.942 | ||||
Yes | 42.7 | 45.3 | 46.3 | 44.8 | |
No | 57.3 | 54.7 | 53.7 | 55.2 | |
Smoked at least 100 cigarettes in life (%) | 0.018 | ||||
Yes | 40.3 | 48.9 | 46.4 | 33.1 | |
No | 59.7 | 51.1 | 53.6 | 66.9 | |
Had at least 12 alcohol drinks in a year (%) | 0.174 | ||||
Yes | 68.2 | 75.0 | 65.6 | 72.5 | |
No | 31.8 | 25.0 | 34.4 | 27.5 | |
Blood urea nitrogen (mg/dL) | 5.0 ± 1.6 | 5.1 ± 1.8 | 4.9 ± 1.8 | 4.6 ± 1.2 | 0.036 |
Serum uric acid (umol/L) | 269.4 ± 68.0 | 297.3 ± 72.0 | 301.1 ± 72.5 | 291.6 ± 60.9 | < 0.001 |
Serum phosphorus (mg/dL) | 1.3 ± 0.2 | 1.3 ± 0.1 | 1.2 ± 0.2 | 1.2 ± 0.2 | < 0.001 |
Serum calcium (mg/dL) | 2.4 ± 0.1 | 2.4 ± 0.1 | 2.4 ± 0.1 | 2.3 ± 0.1 | 0.005 |
Sex hormone binding globulin (nmol/L) | 75.6 ± 36.6 | 61.7 ± 45.7 | 49.6 ± 31.6 | 70.6 ± 43.2 | < 0.001 |
Lumbar bone mineral density (mg/cm2) | 936.2 ± 138.8 | 964.3 ± 137.3 | 994.4 ± 136.6 | 1051.7 ± 141.0 | < 0.001 |